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<正>膝骨关节炎(KOA)是好发于中老年人的一种慢性疾病,出现关节软骨退变、骨质增生及骨赘、滑膜炎,最终导致关节间隙狭窄或消失[1]。临床表现为关节疼痛、僵硬及进行性活动受限,甚至导致关节畸形与残疾,严重影响患者的生活质量,造成了巨大的精神压力和经济负担。目前KOA的发病机制尚不完全清楚,有关KOA疼痛和运动功能障碍的机制也未完全阐明,Sharma[2]认为KOA可能与关节组织中分解和合成代谢变化之间的失衡有关。
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基本信息:
中图分类号:R684.3;R445.2
引用信息:
[1]刘玥,万兵,李红,等.膝骨关节炎髌下脂肪垫MRI多模态评估的研究进展[J].中国老年学杂志,2026,46(15):2865-2870.
基金信息:
2022年度湖北省教育厅科学研究计划项目(B2022032); 2024年度湖北省教育厅科学研究计划指导性项目(B2024023); 2024年度肿瘤微环境与免疫治疗湖北省重点实验室(三峡大学)开放基金(第二批)课题(2024ZLKF2-18)
2026-08-10
2026-08-10