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目的 探讨人工智能(AI)辅助肺纯磨玻璃结节(pGGN)吸收率、体积、短径、长径及CT值在pGGN近期随访中的应用价值。方法 回顾性分析2022年9月至2024年9月于瑞安市人民医院接受低剂量胸部CT检查且随访时间≥1年的pGGN患者265例(共869枚结节),剔除34枚假结节后，最终纳入835枚。按结节大小分为<5 mm组(667枚)、5～8 mm组(105枚)、>8 mm组(63枚)。入组时及随访6个月、1年，采用深睿16 AI软件分析各组结节的吸收率、体积、大小及CT值变化。结果 3组pGGN随访6个月、1年吸收率组间及组内同时间段比较差异均无统计学意义(均P>0.05)。<5 mm组随访6个月与1年pGGN体积、短径、长径增大率无显著差异(P>0.05)。5～8 mm组随访6个月与1年pGGN短径、长径增大率比较无显著差异(P>0.05),随访1年体积增大率显著高于6个月(P<0.05)。>8 mm组随访1年pGGN体积、短径、长径增大率均显著高于6个月(P<0.05)。5～8 mm组随访6个月与1年pGGN体积增大率、随访1年短径和长径增大率均显著高于<5 mm组(P<0.05)。>8 mm组随访6个月与1年pGGN体积、短径和长径增大率均显著高于<5 mm组(P<0.05)。>8 mm组随访6个月与1年pGGN体积增大率、随访1年短径和长径增大率均显著高于5～8 mm组(P<0.05)。5～8 mm组1年、≥8 mm组相同时间段(6个月、1年)体积增大率分别与短径增大率、长径增大率比较，差异均有统计学意义(P<0.05)。<5 mm组不同随访时间CT值差异无统计学意义(P<0.05)。5～8 mm组随访1年CT值显著高于入组时、随访6个月及<5 mm组随访1年(P<0.05)。>8 mm组随访6个月CT值显著高于入组时及<5 mm组和5～8 mm组随访6个月(P<0.05)。>8 mm组随访1年CT值显著高于入组时、随访6个月及<5 mm组和5～8 mm组随访1年(P<0.05)。AI诊断假结节率为3.91%(34/869),高危结节诊断率为37.28%(324/869);6个月、1年有手术指征者的病理符合率分别为9.88%(32/324)、10.03%(33/319),差异无统计学意义(P>0.05)。结论 不同大小pGGN随访6个月、1年吸收率相近；<5 mm组1年随访、5～8 mm组6个月随访时CT值、短径、长径相对稳定，而5～8 mm组1年随访、>8 mm组6个月随访时已存在CT值增高、体积增大的风险。AI辅助观察pGGN体积变化的价值优于单纯径线测量，但假结节率仍需人工识别，手术指征病理符合率有待进一步验证与更新。
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基本信息:
中图分类号:R563
引用信息:
[1]薛卫宽,黄福辉,张福滨,等.AI辅助诊断在肺纯磨玻璃结节近期随访中的应用价值[J].中国老年学杂志,2026,46(15):2739-2743.
基金信息:
瑞安市科技局科研项目(MS2022038)
2026-08-10
2026-08-10